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Toxicology

We offer in vivo acute, long-term toxicology testing, according with the OECD guidelines. This toxicological test are necessary for registration chemical substances, for instance in accordance with the Regulation No. 1907/2006 of the European Parliament, of the Council of December 2006 (REACH Annex VIII, IX, X), Regulation No. 1272/2008 of the European Parliament, of the Council of 16 December 2008 (CLP).

The List of tests we conduct in our laboratories:

  • Acute Oral Toxicity – Fixed Dose Procedure OECD 420
  • Acute Oral Toxicity – Acute Toxic Class Method OECD 423
  • Acute Oral Toxicity – Up-,-Down-Procedure (UDP) OECD 425
  • Acute Dermal Toxicity: Fixed Dose Procedure OECD 402
  • Acute Dermal Irritation/Corrosion OECD 404
  • Acute Eye Irritation/Corrosion OECD 405
  • Local lymph node assay: BRDU-ELISA OECD 442B
  • Skin Sensitization OECD 406
  • Repeated Dose 28-Day Toxicity Study in Rodents OECD 407
  • Repeated Dose Dermal Toxicity: 21/28-day Study OECD 410
  • Repeated dose 90-day toxicity study in rodents OECD 408
  • Subchronic Dermal Toxicity: 90-day Study OECD 411
  • Chronic Toxicity Studies OECD 452
  • Carcinogenicity studies OECD 451
  • Combined chronic toxicity\carcinogenicity studies OECD 453
  • Prenatal developmental toxicity study OECD 414
  • Reproduction/Developmental Toxicity Screening Test OECD 421
  • Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test OECD 422
  • Extended one-generation reproductive toxicity study OECD 443
  • Two-Generation Reproduction Toxicity Study OECD 416
  • Neurotoxicity Study in Rodents OECD 424
  • Rodent Dominant Lethal Test OECD 478
  • Bacterial Reverse Mutation Test OECD 471
  • In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene OECD 490

We have our own animal facility and in vitro laboratories that are GLP-certified for testing mentioned above.

Are you looking for another OECD test? Please send us a query!